Protein sequencing

Although the general structure of proteins is encoded by the sequence of its amino acids, the full characterization of the structure and associated biological functionality is not completed with the determination of the simple sum of amino acids but is subject to a series of very complex analyses.​

For any protein-based drug, characterization of the theoretically expected primary structure is of paramount importance and should always be the first pillar of a detailed structural analysis of your biologic or biosimilar.​
Our comprehensive analytical portfolio includes a variety of state-of-the-art bioanalytical services to identify the exact amino acid sequence, N- and C-terminal modifications, molecular weight as well as the identification of potential mutations.​

Our vast experience and deep knowledge in this field allows us to guide you through the variety of available methods and help you find the optimal analytical solution for your project.​

In accordance with your needs, we adapt and, if required, qualify (according to ICH guidelines) our platform methods tailored to your API, its individual formulation matrix and your distinct analytical question. 

Get in contact with us to find the optimal strategy for your project and to speak directly from scientist to scientist.