DNA/RNA Sequencing
DNA/RNA sequencing
Sequence analysis of DNA and RNA is an indispensable method for answering a variety of questions that arise during the development and production of biologics. Starting from the identification of all integration sites of your gene of interest within the genome of your cell line to the validation of the genome integrity of your gene therapy vector, we offer many methods to support you in all stages of your biological drug development and production.
Our analytical service provides accurate and reliable nucleic acid analyses for a wide range of key questions, including integration site and monoclonality analyses, sequence verification of highly repetitive or similar sequences, gene copy number determination, the structural analysis of tandem repeats, genome integrity analysis of gene therapy vectors, and many more.
With our next-generation sequencing device from Oxford Nanopore Technologies (ONT) we are prepared for high-throughput DNA/RNA analysis, with fast turnaround times to deliver the highest quality data. Our analytical service is designed to meet the needs of researchers, biotech and pharmaceutical companies. We have a proven track record of delivering high-quality data and exceptional customer service.
In accordance with your needs, we adapt our platform methods tailored to your product, its individual formulation matrix and your distinct analytical question.
Get in contact with us to quickly find the optimal setup for your analytical challenge and to speak directly from expert to expert.
Our capabilities
- TCR sequencing
- 16S sequencing
- Long read sequencing (ONT)
- Genome integrity analysis (truncations, duplications, fusions, etc.)
- Amplicon and vector/plasmid characterization
- Analysis of repetitive genetic elements
- poly(A) characterization
- Qualitative and quantitative analysis of process-related DNA contaminations
bioanalytical services
- Genome integrity analysis of gene therapeutics (ONT)
- Detection and quantification of host cell DNA impurities (ONT)
- Empty/full vector quantification (qPCR, ONT)
Tell us about your project
We‘ll advice you to define your assay needs
Technologies used
- Oxford Nanopore Technologies sequencing (ONT)
- Quantitative PCR (qPCR)
Please reach out to Our Expert Tobias Luttermann for all inquiries concerning DNA or RNA analysis.
Phone: +49 (0)521 329 363 48
Mail: Tobias.Luttermann@Biofidus.com