Small Molecule & Spent Media Analysis

The analysis and understanding of small molecules is crucial to the production process of biopharmaceuticals or other molecules produced in eukaryotic or prokaryotic cells.

The analysis aids in detection of substrate limitations or the accumulation of cytotoxic molecules. At Biofidus we offer standardized assays for the analysis of almost 40 different media components.

In customized assays we can extend this portfolio to almost any molecule according to client requirements.

In addition to the analysis of fresh or spent media, we also offer customized metabolomics studies or analysis of small molecule pharmaceuticals by LC- and GC-MS.

  • Amino acids by LC-FLD
  • Vitamins and vitaminoids by LC-FLD/UV/MS
  • Organic acids by LC-MS
  • Ammonium
  • Glucose / lactate
  • Pyruvate
  • Cholesterol
  • RNA- and DNA-content
  • Endotoxin
  • Osmolarity
  • Dipeptides by LC-MS
  • Fatty acids by LC-MS
  • Nucleobases by LC-FLD
  • Leachables and extractables
  • Surfactants by GC-FID
  • Metabolomic studies by LC- and GC-MS